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Persistent or severe symptoms should always be assessed by a clinician

Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial

Along with probiotics and nutrients, these peptides may directly influence bone metabolism and help prevent osteoporosis

Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide are growth factors that can cross the bloodbrain barrier GLP-1 and GIP are peptide hormones and growth factors that play important physiological signaling roles to control cell metabolism and energy utilization (Finan et al., 2016)

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In the original 2015 Cell Metabolism paper, MOTS-c activated AMPK, improved insulin sensitivity in diet-induced obese mice, and reduced age-related insulin resistance in older animals [2]